Development of pulmonary arterial hypertension in mice over-expressing S100A4/Mts1 is specific to females

<p>Abstract</p> <p>Background</p> <p>Idiopathic and familial forms of pulmonary arterial hypertension (PAH) occur more frequently in women than men. However, the reason for this remains unknown. Both the calcium binding protein S100A4/Mts1 (Mts1) and its endogenous rece...

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Bibliographic Details
Main Authors: Dempsie Yvonne, Nilsen Margaret, White Kevin, Mair Kirsty M, Loughlin Lynn, Ambartsumian Noona, Rabinovitch Marlene, MacLean Margaret R
Format: Article
Language:English
Published: BMC 2011-12-01
Series:Respiratory Research
Online Access:http://respiratory-research.com/content/12/1/159