Co-Occurring Atomic Contacts for the Characterization of Protein Binding Hot Spots.

A binding hot spot is a small area at a protein-protein interface that can make significant contribution to binding free energy. This work investigates the substantial contribution made by some special co-occurring atomic contacts at a binding hot spot. A co-occurring atomic contact is a pair of ato...

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Bibliographic Details
Main Authors: Qian Liu, Jing Ren, Jiangning Song, Jinyan Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4684219?pdf=render