Cigarette smoke extract is a Nox agonist and regulates ENaC in alveolar type 2 cells

Cigarette smoke extract is a Nox agonist and regulates ENaC in alveolar type 2 cells

There is considerable evidence that cigarette smoking is the primary etiology of chronic obstructive pulmonary disease (COPD), and that oxidative stress occurs in COPD with the family of tissue nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (Nox) enzymes playing a significant role in lu...

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Bibliographic Details
Main Authors: Abdel A. Alli, My N. Helms, Nicholle M. Johnson, Charles A. Downs
Format: Article
Language:English
Published: AIMS Press 2016-08-01
Series:AIMS Molecular Science
Subjects:
Nox2
Nox4
COPD
lung injury
cell signaling
Online Access:http://www.aimspress.com/Molecular/article/939/fulltext.html

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http://www.aimspress.com/Molecular/article/939/fulltext.html

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