Inhibition of ghrelin o-acyltransferase attenuated lipotoxicity by inducing autophagy via AMPK–mTOR pathway

Inhibition of ghrelin o-acyltransferase attenuated lipotoxicity by inducing autophagy via AMPK–mTOR pathway

Shaoren Zhang, Yuqing Mao, Xiaoming Fan Department of Gastroenterology and Hepatology, Jinshan Hospital of Fudan University, Shanghai, China Background: Nonalcoholic fatty liver disease (NAFLD) has been considered the most commonly occurring chronic hepatopathy in the world. Ghrelin o-acyltransfer...

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Bibliographic Details
Main Authors: Zhang S, Mao Y, Fan X
Format: Article
Language:English
Published: Dove Medical Press 2018-04-01
Series:Drug Design, Development and Therapy
Subjects:
Ghrelin O-Acyltransferase (GOAT)
High fat diet (HFD)
Free fatty acid (FFA)
Nonalcoholic fatty liver disease (NAFLD)
Online Access:https://www.dovepress.com/inhibition-of-ghrelin-o-acyltransferase-attenuated-lipotoxicity-by-ind-peer-reviewed-article-DDDT

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https://www.dovepress.com/inhibition-of-ghrelin-o-acyltransferase-attenuated-lipotoxicity-by-ind-peer-reviewed-article-DDDT

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