β-glucan protects against necrotizing enterocolitis in mice by inhibiting intestinal inflammation, improving the gut barrier, and modulating gut microbiota

β-glucan protects against necrotizing enterocolitis in mice by inhibiting intestinal inflammation, improving the gut barrier, and modulating gut microbiota

Abstract Background Necrotizing enterocolitis (NEC) is a devastating gastrointestinal disease with high morbidity and mortality, affecting preterm infants especially those with very low and extremely low birth weight. β-glucan has manifested multiple biological effects including anti-inflammatory, r...

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Bibliographic Details
Main Authors: Xingdao Zhang, Yuni Zhang, Yu He, Xingwang Zhu, Qing Ai, Yuan Shi
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Journal of Translational Medicine
Subjects:
β-glucan
Inflammatory cytokines
Tight junctions
Intestinal microbiota
TLR4-NF-κB
Online Access:https://doi.org/10.1186/s12967-022-03866-x

Internet

https://doi.org/10.1186/s12967-022-03866-x

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