Susceptibility to hypertension based on MTHFR rs1801133 single nucleotide polymorphism and MTHFR promoter methylation

Susceptibility to hypertension based on MTHFR rs1801133 single nucleotide polymorphism and MTHFR promoter methylation

BackgroundThe aetio-pathologenesis of hypertension is multifactorial, encompassing genetic, epigenetic, and environmental factors. The combined effect of genetic and epigenetic changes on hypertension is not known. We evaluated the independent and interactive association of MTHFR rs1801133 single nu...

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Bibliographic Details
Main Authors: Ming-Huang Chiu, Chia-Hsiu Chang, Disline Manli Tantoh, Tsui-Wen Hsu, Chih-Hsuan Hsiao, Ji-Han Zhong, Yung-Po Liaw
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
MTHFR
promoter methylation
rs1801133
hypertension
susceptibility
interaction
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2023.1159764/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2023.1159764/full

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