Epidermal growth factor receptor and STAT3 signal through KRAS have mutually opposite effects on CTEN

Background: C-terminal tensin-like (CTEN) is a protein located at focal adhesions and has been reported to be an oncogene in the colon, breast, lung, and gastric cancer. In this study, we investigated whether two other proposed mechanisms, i.e., epidermal growth factor receptor (EGFR) and Signal tra...

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Bibliographic Details
Main Authors: Saleh AlGhamdi, Salih Ibrahim, Kanwal Balloch, Darryl Jackson, Mohammad Ilyas
Format: Article
Language:English
Published: Discover STM Publishing Ltd 2021-06-01
Series:Journal of Biochemical and Clinical Genetics
Subjects:
Online Access:http://www.ejmanager.com/fulltextpdf.php?mno=98824