Accurate prediction of functional states of cis-regulatory modules reveals common epigenetic rules in humans and mice

Accurate prediction of functional states of cis-regulatory modules reveals common epigenetic rules in humans and mice

Abstract Background Predicting cis-regulatory modules (CRMs) in a genome and their functional states in various cell/tissue types of the organism are two related challenging computational tasks. Most current methods attempt to simultaneously achieve both using data of multiple epigenetic marks in a...

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Bibliographic Details
Main Authors: Pengyu Ni, Joshua Moe, Zhengchang Su
Format: Article
Language:English
Published: BMC 2022-10-01
Series:BMC Biology
Subjects:
cis-regulatory modules
Enhancers
Functional states
Machine-learning
Predictions
Online Access:https://doi.org/10.1186/s12915-022-01426-9

Internet

https://doi.org/10.1186/s12915-022-01426-9

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