CD45 immunoaffinity depletion of vesicles from Jurkat T cells demonstrates that exosomes contain CD45: no evidence for a distinct exosome/HIV-1 budding pathway

<p>Abstract</p> <p>The presence of relatively high levels of cellular protein contamination in density-purified virion preparations is a confounding factor in biochemical analyses of HIV and SIV produced from hematopoietic cells. A major source of this contamination is from vesicle...

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Bibliographic Details
Main Authors: Ott David E, Shatzer Teresa, Coren Lori V
Format: Article
Language:English
Published: BMC 2008-07-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/5/1/64