Brain Microvascular Endothelial Cell-Derived Exosomes Protect Neurons from Ischemia–Reperfusion Injury in Mice

Brain Microvascular Endothelial Cell-Derived Exosomes Protect Neurons from Ischemia–Reperfusion Injury in Mice

Stroke often results in neurological and neuropsychiatric sequela. Exosomes derived from brain endothelial cells (EC-Exo) protect neurons from hypoxic injury. However, the biological role of exosomes in apoptosis and synaptic plasticity remains unclear. This research aimed to assess whether cerebral...

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Bibliographic Details
Main Authors: Jin Sun, Qing Yuan, Lichen Guo, Guangxu Xiao, Tong Zhang, Bing Liang, Rongmei Yao, Yan Zhu, Yue Li, Limin Hu
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Pharmaceuticals
Subjects:
brain endothelial cells
exosomes
ischemic stroke
synaptic plasticity
apoptosis
Online Access:https://www.mdpi.com/1424-8247/15/10/1287

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https://www.mdpi.com/1424-8247/15/10/1287

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