Pharmacological Modulators of Tau Aggregation and Spreading

Tauopathies are neurodegenerative disorders characterized by the deposition of aggregates composed of abnormal tau protein in the brain. Additionally, misfolded forms of tau can propagate from cell to cell and throughout the brain. This process is thought to lead to the templated misfolding of the n...

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Bibliographic Details
Main Authors: Antonio Dominguez-Meijide, Eftychia Vasili, Tiago Fleming Outeiro
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Brain Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3425/10/11/858