SOS genes are rapidly induced while translesion synthesis polymerase activity is temporally regulated

SOS genes are rapidly induced while translesion synthesis polymerase activity is temporally regulated

The DNA damage inducible SOS response in bacteria serves to increase survival of the species at the cost of mutagenesis. The SOS response first initiates error-free repair followed by error-prone repair. Here, we have employed a multi-omics approach to elucidate the temporal coordination of the SOS...

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Bibliographic Details
Main Authors: Olaug Elisabeth Torheim Bergum, Amanda Holstad Singleton, Lisa Marie Røst, Antoine Bodein, Marie-Pier Scott-Boyer, Morten Beck Rye, Arnaud Droit, Per Bruheim, Marit Otterlei
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Microbiology
Subjects:
SOS response
translesion synthesis
transcriptomics
proteomics
metabolomics
ciprofloxacin
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2024.1373344/full

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https://www.frontiersin.org/articles/10.3389/fmicb.2024.1373344/full

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