Mechanism of Cancer Growth Suppression of Alpha-Fetoprotein Derived Growth Inhibitory Peptides (GIP): Comparison of GIP-34 versus GIP-8 (AFPep). Updates and Prospects

The Alpha-fetoprotein (AFP) derived Growth Inhibitory Peptide (GIP) is a 34-amino acid segment of the full-length human AFP molecule that inhibits tumor growth and metastasis. The GIP-34 and its carboxy-terminal 8-mer segment, termed GIP-8, were found to be effective as anti-cancer therapeutic pepti...

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Bibliographic Details
Main Author: Gerald J. Mizejewski
Format: Article
Language:English
Published: MDPI AG 2011-06-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/3/2/2709/