Excessive SOX8 reprograms energy and iron metabolism to prime hepatocellular carcinoma for ferroptosis

Excessive SOX8 reprograms energy and iron metabolism to prime hepatocellular carcinoma for ferroptosis

Lipid peroxidation and redox imbalance are hallmarks of ferroptosis, an iron-dependent form of cell death. Growing evidence suggests that dysregulation in glycolipid metabolism and iron homeostasis substantially contribute to the development of hepatocellular carcinoma (HCC). However, there is still...

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Manylion Llyfryddiaeth
Prif Awduron: Xue Yang, Chun Gu, Jingshu Cai, Feiyang Li, Xing He, Lunan Luo, Wengan Xiao, Boyan Hu, Jing Hu, Hao Qian, Shangqing Ren, Lin Zhang, Xianjun Zhu, Lu Yang, Jing Yang, Zhenglin Yang, Yi Zheng, Xiang Huang, Ziyan Wang
Fformat: Erthygl
Iaith:English
Cyhoeddwyd: Elsevier 2024-02-01
Cyfres:Redox Biology
Pynciau:
SOX8
Glycolipid metabolism
Ferroptosis
Iron metabolism
HCC
Mynediad Ar-lein:http://www.sciencedirect.com/science/article/pii/S2213231723004032

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http://www.sciencedirect.com/science/article/pii/S2213231723004032

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