Safety and pharmacokinetics of docetaxel in combination with pegvorhyaluronidase alfa in patients with non‐small cell lung cancer

Safety and pharmacokinetics of docetaxel in combination with pegvorhyaluronidase alfa in patients with non‐small cell lung cancer

Abstract This open‐label, phase Ib study (NCT02346370) assessed the effect of pegvorhyaluronidase alfa (PVHA; PEGPH20) on the plasma pharmacokinetics (PKs) and safety of docetaxel in 15 patients with stage IIIB/IV non‐small cell lung cancer (NSCLC). The docetaxel PK profile from this study was consi...

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Bibliographic Details
Main Authors: Thomas Heineman, Megan Baumgart, Charvi Nanavati, Nash Gabrail, Scott A. Van Wart, Donald E. Mager, Daniel C. Maneval, Anas M. Fathallah, Rose E. Sekulovich
Format: Article
Language:English
Published: Wiley 2021-09-01
Series:Clinical and Translational Science
Online Access:https://doi.org/10.1111/cts.13041

Internet

https://doi.org/10.1111/cts.13041

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