Engineering of a NIR-activable hydrogel-coated mesoporous bioactive glass scaffold with dual-mode parathyroid hormone derivative release property for angiogenesis and bone regeneration

Engineering of a NIR-activable hydrogel-coated mesoporous bioactive glass scaffold with dual-mode parathyroid hormone derivative release property for angiogenesis and bone regeneration

Osteogenesis, osteoclastogenesis, and angiogenesis play crucial roles in bone regeneration. Parathyroid hormone (PTH), an FDA-approved drug with pro-osteogenic, pro-osteoclastogenic and proangiogenic capabilities, has been employed for clinical osteoporosis treatment through systemic intermittent ad...

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Bibliographic Details
Main Authors: Shi Liu, Zhengzhe Han, Ji-Na Hao, Dapeng Zhang, Xianglong Li, Yuanyuan Cao, Jinghuan Huang, Yongsheng Li
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2023-08-01
Series:Bioactive Materials
Subjects:
Parathyroid hormone
Dual-mode release
Thermosensitive hydrogel
Angiogenesis
Bone regeneration
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X23000464

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http://www.sciencedirect.com/science/article/pii/S2452199X23000464

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