Nanoparticulate carbon black in cigarette smoke induces DNA cleavage and Th17-mediated emphysema

Chronic inhalation of cigarette smoke is the major cause of sterile inflammation and pulmonary emphysema. The effect of carbon black (CB), a universal constituent of smoke derived from the incomplete combustion of organic material, in smokers and non-smokers is less known. In this study, we show tha...

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Bibliographic Details
Main Authors: Ran You, Wen Lu, Ming Shan, Jacob M Berlin, Errol LG Samuel, Daniela C Marcano, Zhengzong Sun, William KA Sikkema, Xiaoyi Yuan, Lizhen Song, Amanda Y Hendrix, James M Tour, David B Corry, Farrah Kheradmand
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-10-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/09623