Disruption of the grid cell network in a mouse model of early Alzheimer’s disease

It remains poorly understood how the onset of Alzheimer’s disease affects spatial cognition. Here, the authors report that spatial coding in grid cells deteriorates over time in a mouse model of Alzheimer’s disease during the early stages of pathology while place cell and head direction coding remai...

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Bibliographic Details
Main Authors: Johnson Ying, Alexandra T. Keinath, Raphael Lavoie, Erika Vigneault, Salah El Mestikawy, Mark P. Brandon
Format: Article
Language:English
Published: Nature Portfolio 2022-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-28551-x