MiRNAs Expression Profiling in Raw264.7 Macrophages after Nfatc1-Knockdown Elucidates Potential Pathways Involved in Osteoclasts Differentiation

MiRNAs Expression Profiling in Raw264.7 Macrophages after Nfatc1-Knockdown Elucidates Potential Pathways Involved in Osteoclasts Differentiation

Differentiation of macrophages toward osteoclasts is crucial for bone homeostasis but can be detrimental in disease states, including osteoporosis and cancer. Therefore, understanding the osteoclast differentiation process and the underlying regulatory mechanisms may facilitate the identification of...

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Bibliographic Details
Main Authors: Roberta Russo, Francesca Zito, Nadia Lampiasi
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Biology
Subjects:
osteoclastogenesis
differential expression
MAPK pathway
NFATc1
PCR arrays
siRNA transfection
Online Access:https://www.mdpi.com/2079-7737/10/11/1080

Internet

https://www.mdpi.com/2079-7737/10/11/1080

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