Pancreatic Acinar Cell Preparation for Oxygen Consumption and Lactate Production Analysis

Mitochondrial dysfunction is a principal feature of acute pancreatitis (AP) although the underlying mechanisms are still unclear. AP precipitants induce Ca2+-dependent formation of the mitochondrial permeability transition pore (MPTP) in pancreatic acinar cells (PACs), leading to ATP depletion and n...

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Bibliographic Details
Main Authors: Jane Armstrong, Robert Sutton, David Criddle
Format: Article
Language:English
Published: Bio-protocol LLC 2020-05-01
Series:Bio-Protocol
Online Access:https://bio-protocol.org/en/bpdetail?id=3627&type=0