Immunogenicity of 60 novel latency-related antigens of Mycobacterium tuberculosis

Immunogenicity of 60 novel latency-related antigens of Mycobacterium tuberculosis

The aim of our work here was to evaluate the immunogenicity of 60 mycobacterial antigens, some of which have not been previously assessed, notably a novel series of in vivo-expressed M.tuberculosis (IVE-TB) antigens. We enrolled 505 subjects and separated them in individuals with and without latent...

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Bibliographic Details
Main Authors: Mªdel Mar eSerra Vidal, Irene eLatorre, Kees eFranken, Malú eDe Souza-Galvao, Irma eCasas, josé eMaldonado, Cèlia eMilà, Jordi eSolsona, M.Ángeles eJiménez-Fuentes, Neus eAltet, Alicia eLacoma, Juan eRuiz-Manzano, Vicente eAusina, Cristina ePrat, Tom H.M. Ottenhoff, Jose eDomínguez
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-10-01
Series:Frontiers in Microbiology
Subjects:
Tuberculosis
immune response
Interferon-γ
latent tuberculosis infection
antigenic stimulation
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2014.00517/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2014.00517/full

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