Vaccine-Induced Immunity Elicited by Microneedle Delivery of Influenza Ectodomain Matrix Protein 2 Virus-like Particle (M2e VLP)-Loaded PLGA Nanoparticles

Vaccine-Induced Immunity Elicited by Microneedle Delivery of Influenza Ectodomain Matrix Protein 2 Virus-like Particle (M2e VLP)-Loaded PLGA Nanoparticles

This study focused on developing an influenza vaccine delivered in polymeric nanoparticles (NPs) using dissolving microneedles. We first formulated an influenza extracellular matrix protein 2 virus-like particle (M2e VLP)-loaded with poly(lactic-co-glycolic) acid (PLGA) nanoparticles, yielding M2e5x...

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Bibliographic Details
Main Authors: Keegan Braz Gomes, Sharon Vijayanand, Priyal Bagwe, Ipshita Menon, Akanksha Kale, Smital Patil, Sang-Moo Kang, Mohammad N. Uddin, Martin J. D’Souza
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:International Journal of Molecular Sciences
Subjects:
influenza
vaccine
microneedles
nanoparticles
VLP
PLGA
Online Access:https://www.mdpi.com/1422-0067/24/13/10612

Internet

https://www.mdpi.com/1422-0067/24/13/10612

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