The Notch signaling pathway: a potential target for cancer immunotherapy

The Notch signaling pathway: a potential target for cancer immunotherapy

Abstract Dysregulation of the Notch signaling pathway, which is highly conserved across species, can drive aberrant epigenetic modification, transcription, and translation. Defective gene regulation caused by dysregulated Notch signaling often affects networks controlling oncogenesis and tumor progr...

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Bibliographic Details
Main Authors: Xinxin Li, Xianchun Yan, Yufeng Wang, Balveen Kaur, Hua Han, Jianhua Yu
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Journal of Hematology & Oncology
Subjects:
Immune cells
Cancer immunotherapy
Notch signaling
Tumor-associated macrophages
Chimeric antigen receptor (CAR)
Immune checkpoint
Online Access:https://doi.org/10.1186/s13045-023-01439-z

Internet

https://doi.org/10.1186/s13045-023-01439-z

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