Nanostructured lipid carriers mediated transdermal delivery of trandolapril as an impeccable therapeutic approach against hypertension: Development, characterization and in vivo evaluation

The study aimed to design trandolapril-embedded nanostructured lipid carriers (NLCs) transdermal patch and evaluate its in vitro drug permeation, bioavailability and pharmacokinetics. Trandolapril, a poorly soluble drug with antihypertensive activity, was used and investigated in the development of...

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Bibliographic Details
Main Authors: Ramankit Jaiswal, Rita Wadetwar
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:OpenNano
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352952023000233