Analysis on heterogeneity of hepatocellular carcinoma immune cells and a molecular risk model by integration of scRNA-seq and bulk RNA-seq

Analysis on heterogeneity of hepatocellular carcinoma immune cells and a molecular risk model by integration of scRNA-seq and bulk RNA-seq

BackgroundStudies have shown that hepatocellular carcinoma (HCC) heterogeneity is a main cause leading to failure of treatment. Technology of single-cell sequencing (scRNA) could more accurately reveal the essential characteristics of tumor genetics.MethodsFrom the Gene Expression Omnibus (GEO) data...

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Bibliographic Details
Main Authors: Xiaorui Liu, Jingjing Li, Qingxiang Wang, Lu Bai, Jiyuan Xing, Xiaobo Hu, Shuang Li, Qinggang Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Immunology
Subjects:
hcc
ScRNA-seq
riskscore
autophagy
molecular subtypes
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1012303/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1012303/full

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