Using targeted fetal rat testis genomic and endocrine alterations to predict the effects of a phthalate mixture on the male reproductive tract

Administration of phthalates in utero disrupts gene expression and hormone levels in the fetal rat testis, which are key events in an Adverse Outcome Pathway (AOP) for the Phthalate Syndrome. These measures can be used to predict the postnatal adverse effects of phthalate esters (PEs) on male rat se...

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Bibliographic Details
Main Authors: L. Earl Gray, Jr, Christy S. Lambright, Nicola Evans, Jermaine Ford, Justin M. Conley
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Current Research in Toxicology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666027X24000331