Best Supportive Care Versus Whole-Brain Irradiation, Chemotherapy Alone, or WBRT Plus Chemotherapy in Patients With Brain Metastases From Small-Cell Lung Cancer: A Case-Controlled Analysis

Best Supportive Care Versus Whole-Brain Irradiation, Chemotherapy Alone, or WBRT Plus Chemotherapy in Patients With Brain Metastases From Small-Cell Lung Cancer: A Case-Controlled Analysis

BackgroundWBRT and systemic chemotherapy are the mainstay treatments for small-cell lung cancer (SCLC) brain metastases (BM). However, current recommendations are mainly based on evidence from retrospective analyses. A recent randomized trial found no benefits from WBRT compared with best supportive...

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Bibliographic Details
Main Authors: Hongwei Li, Ruiqi Xue, Xiaotang Yang, Songye Han, Weihua Yang, Xin Song, Xiaqin Zhang, Jianzhong Cao, Sufang Jia, Weili Wang, Jianhong Lian
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Oncology
Subjects:
small cell lung cancer
brain metastases
whole-brain irradiation
chemotherapy
best supportive care
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.568568/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.568568/full

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