Modulation of insulin-like growth factor-1 receptor and its signaling network for the treatment of cancer: current status and future perspectives
Based on over three decades of pre-clinical data, insulin-like growth factor-1 receptor (IGF-1R) signaling has gained recognition as a promoter of tumorogenesis, driving cell survival and proliferation in multiple human cancers. As a result, IGF-1R has been pursued as a target for cancer treatment....
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2013-04-01
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| Series: | Oncology Reviews |
| Subjects: |