Normal and malignant epithelial cells with stem-like properties have an extended G2 cell cycle phase that is associated with apoptotic resistance

<p>Abstract</p> <p>Background</p> <p>Subsets of cells with stem-like properties have been previously isolated from human epithelial cancers and their resistance to apoptosis-inducing stimuli has been related to carcinoma recurrence and treatment failure. The aim of this...

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Bibliographic Details
Main Authors: Biddle Adrian, Fazil Bilal, Gammon Luke, Costea Daniela, Harper Lisa J, Mackenzie Ian C
Format: Article
Language:English
Published: BMC 2010-04-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/10/166