Effect of sphingosine and phytosphingosine ceramide ratio on lipid arrangement and barrier function in skin lipid models

Effect of sphingosine and phytosphingosine ceramide ratio on lipid arrangement and barrier function in skin lipid models

The lipids in the uppermost layer of the skin, the stratum corneum (SC), play an important role in the skin barrier function. The three main subclasses in the SC lipid matrix are ceramides (CER), cholesterol, and free fatty acids. In inflammatory skin diseases, such as atopic dermatitis and psoriasi...

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Bibliographic Details
Main Authors: Andreea Nădăban, Jannik Rousel, Dounia El Yachioui, Gerrit S. Gooris, Charlotte M. Beddoes, Robert M. Dalgliesh, Marc Malfois, Robert Rissmann, Joke A. Bouwstra
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:Journal of Lipid Research
Subjects:
skin
lipids
ceramides
sphingolipids
cholesterol
stratum corneum
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227523000731

Internet

http://www.sciencedirect.com/science/article/pii/S0022227523000731

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