Structural diversification of bioactive bibenzyls through modular co-culture leading to the discovery of a novel neuroprotective agent

Structural diversification of bioactive bibenzyls through modular co-culture leading to the discovery of a novel neuroprotective agent

Bibenzyls, a kind of important plant polyphenols, have attracted growing attention for their broad and remarkable pharmacological activities. However, due to the low abundance in nature, uncontrollable and environmentally unfriendly chemical synthesis processes, these compounds are not readily acces...

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Bibliographic Details
Main Authors: Yuyu Liu, Xinnan Li, Songyang Sui, Jingshu Tang, Dawei Chen, Yuying Kang, Kebo Xie, Jimei Liu, Jiaqi Lan, Lei Wu, Ridao Chen, Ying Peng, Jungui Dai
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Bibenzyls
Modular co-culture engineering
Promiscuous enzymes
Neuroprotective agent
Aifm3
Dendrobium officinale
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383522004245

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http://www.sciencedirect.com/science/article/pii/S2211383522004245

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