Gram-Positive Bacteria Cell Wall Peptidoglycan Polymers Activate Human Dendritic Cells to Produce IL-23 and IL-1β and Promote T<sub>H</sub>17 Cell Differentiation

Gram-Positive Bacteria Cell Wall Peptidoglycan Polymers Activate Human Dendritic Cells to Produce IL-23 and IL-1β and Promote T<sub>H</sub>17 Cell Differentiation

Gram-positive bacterial infections are a major cause of organ failure and mortality in sepsis. Cell wall peptidoglycan (PGN) is shed during bacterial replication, and <i>Bacillus anthracis</i> PGN promotes a sepsis-like pathology in baboons. Herein, we determined the ability of polymeric...

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Bibliographic Details
Main Authors: Sean Turner, Brent Raisley, Kimberly Roach, Sandra Bajaña, Melissa E. Munroe, Judith A. James, K. Mark Coggeshall, Susan Kovats
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Microorganisms
Subjects:
peptidoglycan
dendritic cell
T helper differentiation
<i>Bacillus anthracis</i>
Online Access:https://www.mdpi.com/2076-2607/11/1/173

Internet

https://www.mdpi.com/2076-2607/11/1/173

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