Single-Cell Sequencing Reveals that DBI is the Key Gene and Potential Therapeutic Target in Quiescent Bladder Cancer Stem Cells

Single-Cell Sequencing Reveals that DBI is the Key Gene and Potential Therapeutic Target in Quiescent Bladder Cancer Stem Cells

Background: Drug resistance and recurrence often develop during the treatment of muscle-invasive bladder cancer (MIBC). The existence of cancer stem cells (CSCs) in MIBC makes the formulation of effective treatment strategies extremely challenging. We aimed to use single-cell RNA sequencing approach...

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Bibliographic Details
Main Authors: Jiaxi Yao, Yue Liu, Jitao Yang, Mengling Li, Simin Li, Bo Zhang, Rui Yang, Yuchong Zhang, Xiaoyu Cui, ChunQing Feng
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Genetics
Subjects:
cancer stem cells
bladder cancer
scRNA-seq
acetaminophen
DBI
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.904536/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2022.904536/full

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