Molecular Landscape of ERBB2 Alterations in 14,956 Solid Tumors

ERBB2 abnormalities frequently occur and serve as rationale therapeutic targets in cancer. In this study, clinical and next-generation sequencing data from 14,956 patients across more than 20 tumor types were collected. A total of 406 (2.7%) patients were identified with ERBB2 amplifications, and 30...

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Bibliographic Details
Main Authors: Hao Wang, Ji Miao, Yazhou Wen, Xihua Xia, Yanan Chen, Mengli Huang, Shiqing Chen, Zhengyi Zhao, Yuzi Zhang, Chunzhu Chen, Xinhua Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Pathology and Oncology Research
Subjects:
Online Access:https://www.por-journal.com/articles/10.3389/pore.2022.1610360/full