Mast cell degranulation impairs pneumococcus clearance in mice via IL-6 dependent and TNF-α independent mechanisms

Mast cell degranulation impairs pneumococcus clearance in mice via IL-6 dependent and TNF-α independent mechanisms

Background: Mast cells participate in immune responses by releasing potent immune system modifiers via degranulation. Due to currently reported controversial roles of mast cells in Streptococcus pneumoniae infections, this study aimed to determine the role and mechanism of mast cells in clearing S. ...

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Bibliographic Details
Main Authors: Jing Yang, Jichao Wang, Xuemei Zhang, Yulan Qiu, Jurong Yan, Si Sun, Yujuan He, Yibing Yin, Wenchun Xu
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:World Allergy Organization Journal
Online Access:http://www.sciencedirect.com/science/article/pii/S1939455119301164

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http://www.sciencedirect.com/science/article/pii/S1939455119301164

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