DNA recognition patterns of the multi-zinc-finger protein CTCF: a mutagenesis study

CCCTC-binding factor (CTCF) is a zinc-finger protein, serving an important part in the genome architecture as well as some biochemical processes. Over 70,000 CTCF binding DNA sites have been detected genome-wide, and most anchors of chromatin loops are demarcated with the CTCF binding. Various prote...

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Bibliographic Details
Main Authors: Jingjing Guo, Ni Li, Jiexiong Han, Fei Pei, Tianyu Wang, Duo Lu, Jiandong Jiang
Format: Article
Language:English
Published: Elsevier 2018-10-01
Series:Acta Pharmaceutica Sinica B
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383518301990