Ketone body β-hydroxybutyrate is an autophagy-dependent vasodilator

Ketone body β-hydroxybutyrate is an autophagy-dependent vasodilator

Autophagy has long been associated with longevity, and it is well established that autophagy reverts and prevents vascular deterioration associated with aging and cardiovascular diseases. Currently, our understanding of how autophagy benefits the vasculature is centered on the premise that reduced a...

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Bibliographic Details
Main Authors: Cameron G. McCarthy, Saroj Chakraborty, Gagandeep Singh, Beng San Yeoh, Zachary J. Schreckenberger, Avinash Singh, Blair Mell, Nicole R. Bearss, Tao Yang, Xi Cheng, Matam Vijay-Kumar, Camilla F. Wenceslau, Bina Joe
Format: Article
Language:English
Published: American Society for Clinical investigation 2021-10-01
Series:JCI Insight
Subjects:
Vascular biology
Online Access:https://doi.org/10.1172/jci.insight.149037

Internet

https://doi.org/10.1172/jci.insight.149037

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