Anti-Prion Systems Block Prion Transmission, Attenuate Prion Generation, Cure Most Prions as They Arise and Limit Prion-Induced Pathology in <i>Saccharomyces cerevisiae</i>

All variants of the yeast prions [PSI+] and [URE3] are detrimental to their hosts, as shown by the dramatic slowing of growth (or even lethality) of a majority, by the rare occurrence in wild isolates of even the mildest variants and by the absence of reproducible benefits of these prions. To deal w...

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Bibliographic Details
Main Authors: Reed B. Wickner, Herman K. Edskes, Moonil Son, Songsong Wu
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Biology
Subjects:
Online Access:https://www.mdpi.com/2079-7737/11/9/1266