Anti-Prion Systems Block Prion Transmission, Attenuate Prion Generation, Cure Most Prions as They Arise and Limit Prion-Induced Pathology in <i>Saccharomyces cerevisiae</i>
All variants of the yeast prions [PSI+] and [URE3] are detrimental to their hosts, as shown by the dramatic slowing of growth (or even lethality) of a majority, by the rare occurrence in wild isolates of even the mildest variants and by the absence of reproducible benefits of these prions. To deal w...
Main Authors: | Reed B. Wickner, Herman K. Edskes, Moonil Son, Songsong Wu |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-08-01
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Series: | Biology |
Subjects: | |
Online Access: | https://www.mdpi.com/2079-7737/11/9/1266 |
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