Detection of antimicrobial impact on gram-negative bacterial cell envelope based on single-cell imaging by scanning electron microscopy

Abstract Rapid determination of drug efficacy against bacterial pathogens is needed to detect potentially resistant bacteria and allow for more rational use of antimicrobials. As an indicator of the antimicrobial effect for rapid detection, we found changes in image brightness in antimicrobial-affec...

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Bibliographic Details
Main Authors: Akiko Hisada, Erino Matsumoto, Ryo Hirano, Mami Konomi, Jacques Yaacoub Bou Khalil, Didier Raoult, Yusuke Ominami
Format: Article
Language:English
Published: Nature Portfolio 2023-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-38198-3