Preparation of human primary macrophages to study the polarization from monocyte-derived macrophages to pro- or anti-inflammatory macrophages at biomaterial interface in vitro

Preparation of human primary macrophages to study the polarization from monocyte-derived macrophages to pro- or anti-inflammatory macrophages at biomaterial interface in vitro

Background/purpose: Testing of dental materials when in contact with innate immune cells has been so far hindered by the lack of proper in vitro models. Human primary monocyte-derived macrophages (MDMs) would be an excellent option to this aim. However, the inability to detach them from the tissue c...

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Bibliographic Details
Main Authors: Ludovica Parisi, Massimiliano Giovanni Bianchi, Benedetta Ghezzi, Eleonora Maurizi, Guido Maria Macaluso, Ovidio Bussolati, Simone Lumetti
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Journal of Dental Sciences
Subjects:
Biocompatible materials
Bone substitutes
Dental implants
Macrophages
Macrophage inflammation
Human
Online Access:http://www.sciencedirect.com/science/article/pii/S199179022300020X

Internet

http://www.sciencedirect.com/science/article/pii/S199179022300020X

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