Computer-aided scoring of erb-b2 receptor tyrosine kinase 2 (HER2) gene amplification status in breast cancer

Computer-aided scoring of erb-b2 receptor tyrosine kinase 2 (HER2) gene amplification status in breast cancer

Background: Identification of HER2 protein overexpression and/or amplification of the HER2 gene are required to qualify breast cancer patients for HER2 targeted therapies. In situ hybridization (ISH) assays that identify HER2 gene amplification function as a stand-alone test for determination of HER...

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Bibliographic Details
Main Authors: Alyson Yoder, Landon J. Inge, Chen-Chun Chen, Vijay R. Marati, Trung Kien Nguyen, Karel Zuiderveld, Jim Martin, Sarah Gladden, Mohammad Saleh Miri, Raghavan Venugopal, Bryan Lopez, Jim Ranger-Moore, Christoph Guetter
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Journal of Pathology Informatics
Subjects:
Image analysis
Algorithm
HER2
Breast cancer
Bright-field ISH
Online Access:http://www.sciencedirect.com/science/article/pii/S2153353922007106

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http://www.sciencedirect.com/science/article/pii/S2153353922007106

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