Isolation and characterisation of a recombinant antibody fragment that binds NCAM1-expressing intervertebral disc cells.

Isolation and characterisation of a recombinant antibody fragment that binds NCAM1-expressing intervertebral disc cells.

Degeneration of the intervertebral discs (IVD) is a leading cause of neck and low back pain. Degeneration begins in the central nucleus pulposus region, leading to loss of IVD osmotic properties. Regeneration approaches include administration of matrix-mimicking scaffolds, cells and/or therapeutic f...

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Bibliographic Details
Main Authors: Claire Cunningham, Akshay Srivastava, Estelle Collin, Sibylle Grad, Mauro Alini, Abhay Pandit, J Gerard Wall
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24349544/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24349544/?tool=EBI

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