TGF-β from the Porcine Intestinal Cell Line IPEC-J2 Induced by Porcine Circovirus 2 Increases the Frequency of Treg Cells via the Activation of ERK (in CD4<sup>+</sup> T Cells) and NF-κB (in IPEC-J2)

TGF-β from the Porcine Intestinal Cell Line IPEC-J2 Induced by Porcine Circovirus 2 Increases the Frequency of Treg Cells via the Activation of ERK (in CD4<sup>+</sup> T Cells) and NF-κB (in IPEC-J2)

Porcine circovirus 2 (PCV2) causes immunosuppression. Piglets infected with PCV2 can develop enteritis. Given that the gut is the largest immune organ, however, the response of the gut’s immune system to PCV2 is still unclear. Here, IPEC-J2 cells with different treatments were co-cultured with PBMC...

Full description

Bibliographic Details
Main Authors: Xuewei Liu, Yang Wang, Cheng Han, Qiuming Li, Xiaolin Hou, Qinye Song, Shuanghai Zhou, Huanrong Li
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Viruses
Subjects:
porcine circovirus 2
intestinal porcine epithelial cells
Foxp3<sup>+</sup> regulatory T cells
TGF-β
ERK
NF-κB
Online Access:https://www.mdpi.com/1999-4915/14/11/2466

Internet

https://www.mdpi.com/1999-4915/14/11/2466

Similar Items