Detection of Ki67 Hot-Spots of Invasive Breast Cancer Based on Convolutional Neural Networks Applied to Mutual Information of H&E and Ki67 Whole Slide Images

Detection of Ki67 Hot-Spots of Invasive Breast Cancer Based on Convolutional Neural Networks Applied to Mutual Information of H&E and Ki67 Whole Slide Images

Ki67 hot-spot detection and its evaluation in invasive breast cancer regions play a significant role in routine medical practice. The quantification of cellular proliferation assessed by Ki67 immunohistochemistry is an established prognostic and predictive biomarker that determines the choice of the...

Full description

Bibliographic Details
Main Authors: Zaneta Swiderska-Chadaj, Jaime Gallego, Lucia Gonzalez-Lopez, Gloria Bueno
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Applied Sciences
Subjects:
Ki67 hot-spot detection
Ki67 labeling index
proliferation index
CNNs
color deconvolution
WSI
Online Access:https://www.mdpi.com/2076-3417/10/21/7761

Internet

https://www.mdpi.com/2076-3417/10/21/7761

Similar Items