Fetal growth restriction in a genetic model of sporadic Beckwith–Wiedemann syndrome

Fetal growth restriction in a genetic model of sporadic Beckwith–Wiedemann syndrome

Beckwith–Wiedemann syndrome (BWS) is a complex imprinting disorder involving fetal overgrowth and placentomegaly, and is associated with a variety of genetic and epigenetic mutations affecting the expression of imprinted genes on human chromosome 11p15.5. Most BWS cases are linked to loss of methyla...

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Bibliographic Details
Main Authors: Simon J. Tunster, Mathew Van de Pette, Hugo D. J. Creeth, Louis Lefebvre, Rosalind M. John
Format: Article
Language:English
Published: The Company of Biologists 2018-11-01
Series:Disease Models & Mechanisms
Subjects:
Beckwith–Wiedemann syndrome
Mouse model
Fetal growth restriction
Placentomegaly
Online Access:http://dmm.biologists.org/content/11/11/dmm035832

Internet

http://dmm.biologists.org/content/11/11/dmm035832

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