Daphnetin ameliorates acute lung injury in mice with severe acute pancreatitis by inhibiting the JAK2–STAT3 pathway

Daphnetin ameliorates acute lung injury in mice with severe acute pancreatitis by inhibiting the JAK2–STAT3 pathway

Abstract Severe acute pancreatitis (SAP) is often associated with pulmonary inflammation leading to acute lung injury. Daphnetin, a natural coumarin derivative, has been reported to exert anti-inflammatory effects. Here, we explored the effect and possible mechanism of daphnetin in a mouse model of...

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Bibliographic Details
Main Authors: Shujun Yang, Yaodong Song, Qiaofang Wang, Yanna Liu, Zhongwei Wu, Xiaojia Duan, Yan Zhang, Xiuqian Bi, Yuanzhang Geng, Sanyang Chen, Changju Zhu
Format: Article
Language:English
Published: Nature Portfolio 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-91008-6

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https://doi.org/10.1038/s41598-021-91008-6

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