Fluidic Flow Enhances the Differentiation of Placental Trophoblast-Like 3D Tissue from hiPSCs in a Perfused Macrofluidic Device

Fluidic Flow Enhances the Differentiation of Placental Trophoblast-Like 3D Tissue from hiPSCs in a Perfused Macrofluidic Device

The human placenta serves as a multifunctional organ to maintain the proper development of a fetus. However, our knowledge of the human placenta is limited due to the lack of appropriate experimental models. In this work, we created an in vitro placental trophoblast-like model via self-organization...

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Bibliographic Details
Main Authors: Pengwei Deng, Kangli Cui, Yang Shi, Yujuan Zhu, Yaqing Wang, Xiaoguang Shao, Jianhua Qin
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
placental model
organ-on-a-chip
trophoblast
perfused 3D culture
hiPSCs
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.907104/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2022.907104/full

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