Accelerated Telomere Shortening in Acromegaly; IGF-I Induces Telomere Shortening and Cellular Senescence.
<h4>Objective</h4>Patients with acromegaly exhibit reduced life expectancy and increased prevalence of age-related diseases, such as diabetes, hypertension, and cardiovascular disease. However, the underlying mechanism has not been fully elucidated. Telomere shortening is reportedly asso...
Asıl Yazarlar: | , , , , , , , , , , , |
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Materyal Türü: | Makale |
Dil: | English |
Baskı/Yayın Bilgisi: |
Public Library of Science (PLoS)
2015-01-01
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Seri Bilgileri: | PLoS ONE |
Online Erişim: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0140189&type=printable |