Detection of PLZF- RARa fusion in patients with Acute Promyelocytic Leukemia

Detection of PLZF- RARa fusion in patients with Acute Promyelocytic Leukemia

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Background and Aim: Acute promyelocytic leukemia (APL) is associated with the t(1517) ,fusing promyelocytic leukemia (PML) and retinoic acid receptor-a (RARa) genes. This disease is uniquely sensitive to treatment with all-trans retinoic acid (ATRA) and highly responsive to conventional chemotherapy...

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Bibliographic Details
Main Authors: M Araghi, K Alimoghadam, N Einollahi, B Chardooli, HR Rahimi, SH Rostami, A Ghavamzadeh
Format: Article
Language:fas
Published: Tehran University of Medical Sciences 2008-09-01
Series:پیاورد سلامت
Subjects:
plzf-rara
pml- rara
acute promyelocytic leukemia (apl)
rt-pcr
Online Access:http://payavard.tums.ac.ir/article-1-148-en.html

Internet

http://payavard.tums.ac.ir/article-1-148-en.html

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